Microneedling at your medical spa is generally well-tolerated, but it can cause some discomfort, which is typically described as mild to moderate. The sensation experienced during the procedure is often likened to light sandpaper being moved across the skin. To minimize discomfort, most medical spas apply a topical numbing cream to the treatment area before beginning the procedure. This anesthetic significantly reduces any pain that might be felt during microneedling. After the treatment, you might experience some redness, swelling, or a sensation similar to a sunburn, but these side effects usually subside within a few days.